![]() ![]() ![]() Although the immunologic assay for canine serum ferritin has been available for over a decade, its value in detecting iron deficiency anemia (IDA) in chronically ill dogs is not reported. Also, serum ferritin is an acute phase reactant and concentrations may be increased with certain neoplastic and inflammatory diseases, which may make diagnosis of concurrent iron deficiency challenging. Because iron is preferentially shunted to hemoglobin (Hb) formation, typical hematologic changes do not occur until late in iron deficiency, long after detrimental effects have occurred. 4,5 In uncomplicated iron deficiency, the serum iron concentration and ferritin are typically low and the TIBC (total iron binding capacity) is usually high. Detection of early iron deficiency, before the appearance of those abnormalities, or iron deficiency in the presence of other diseases (e.g., neoplasia and inflammation) is a diagnostic challenge. Diagnosis of uncomplicated and chronic iron deficiency is based on classic hematologic and biochemical abnormalities such as changes in erythrocyte indices (microcytic, hypochromic anemia) and decreased serum ferritin concentration (table 2). Patty Ewing, DVM, MS, DACVP (Anatomic and Clinical 541-5014Īt Angell Animal Medical Center, the majority of cases of iron deficiency anemia are due to chronic hemorrhage from gastrointestinal tumors. Veterinary Clinic for Low Income Pet Owners.Vet Services Report Cruelty Animal Advocacy Adopt
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